21-Hydroxylase

The RSR 21-hydroxylase autoantibody (21-OH Ab) ELISA kit is intended for use by professional persons only, for the quantitative determination of 21-OH Ab in human serum. Autoimmune destruction of the adrenal cortex is the most common cause of Addison’s disease and autoantibodies to the adrenal specific enzyme steroid 21 hydroxylase are important markers of adrenal autoimmunity. This can be the case if the disease presents as Addison’s disease or as part of the autoimmune polyglandular syndromes (APS) type I or type II.